Rho-associated kinase activity is a biomarker for cardiovascular events
As reported in Hypertension, rho-associated kinase activity is an independent predictor of cardiovascular events. The study involved 633 patients undergoing routine health screening examinations with a median follow-up of 42 months. There were 29 cardiovascular-related deaths, 2 myocardial infarctions, 20 revascularizations, 15 strokes, and 17 hospitalizations for heart failure. The HRs for first cardiovascular event, death, stroke, and revascularization were 2.19, 2.57, 2.14, and 2.68, respectively.
Relationship benefit in women with IHD
As reported in BMC Medicine, women who were married or living with a partner had a decreased risk of mortality (RR=0.72) after the first ischemic heart disease (IHD) event compared to women who were not married or living with a partner. The study involved 734626 women with no history of IHD who were followed for 8.6 y; there were 30747 women with a first IHD event and 2148 deaths.
AGEs increase cardiovascular risk in T2DM
As reported in Diabetes, elevated advanced glycation end products increase the risk for incident cardiovascular events (HR=1.31) in type 2 diabetics (n=218).